Prerequisites: Epid 503 or equivalent; Epid 515 or equivalent; Biostat 503 or equivalent
Description: This course relates genomics to the core public health discipline of epidemiology emphasizing the use of genomics to help describe disease frequency and distribution and to gain insights into biological etiologies. Topics include genetic material in disease, in families and in populations; the investigation of multifactorial traits; model-based linkage analysis; model-free linkage analysis; segregation analysis; allele association and linkage disequilibrium; and gene-gene interactions and gene-environment interactions. Issues related to implementing studies are considered.