mRNA by SNP Browser
If you use the browser, please fill out the registration form.
Comments and suggestions are welcome! Please contact us:
Liming Liang, Wei Chen, or Goncalo Abecasis
Setup file for Windows (last update: 2007.10.29), full dataset (size=513,101,473bytes). In addition to browsing the results by transcript or by position, results can be searched for information on specific SNPs. LD and tag information is provided for SNPs not in our database but evaluated by the International HapMap Consortium.
Setup file for Windows (smaller (LOD>=3) dataset) (last update: 2007.10.12, size=103Mb).
Flat files to use if you want to incorporate the dataset into your own database (last update: 2007.10.12, 466Mb, description included).
Linux executable and full dataset (last update: 2007.10.29, 500Mb). X windows is required.
Description and instructions (last update: 2007.10.29)
References
Dixon AL*, Liang L*, Moffatt MF*, Chen W, Heath S, Wong KCC, Taylor J, Gut I, Farrall M, Lathrop GM, Abecasis GR, and Cookson WOC (2007). A whole-genome association study of global gene expression. Nature Genetics 39:1202-1207.
Moffatt MF*, Kabesch M*, Liang L*, Dixon AL, Strachan D, Heath S, Depner M, von Berg A, Bufe A, Rietschel E, Heinzmann A, Simma B, Frischer T, Willis-Owen SAG, Wong KCC, Illig T, Vogelberg C, Weiland SK, von Mutius E, Abecasis GR3, Farrall M, Gut IG, Lathrop GM, and Cookson WOC (2007) Genetic variants regulating ORMDL3 expression are determinants of susceptibility to childhood asthma. Nature 448:470-473.
*Joint first authors
Update History
2007.10.29 -- Version number increased to 1.0.1. The "query by position" mode is now 10x faster. A Linux version of the browser is now available for download. This update affects the browsers with full dataset only.
2007.10.12 -- Fixed display of the total heritability for each probeset. The previous version displayed an estimate of overall heritability computed before applying the inverse-normal transformation, and was thus slightly different from results in the paper. This fix affects both the browser and flat file downloads.