CoaCC

CoaCC simulates a case-control study using a coalescent framework.  It assumes a haploid sample of cases and a second haploid sample of controls.  Genealogy is generated from these two samples, dependent on the user-specified population history.  From this genealogy a distribution of marker-haplotypes is generated by allowing for marker-mutation and recombinations between marker and gene as well as between markers.

The current version is 1.0.1.  If you use CoaCC please e-mail szoellne@umich.edu or fill out the registration form. The software and files can be downloaded here.