Faculty Profile

Yi Li

Yi Li, PhD

  • M. Anthony Schork Collegiate Professor of Biostatistics
  • Professor, Global Public Health

Li has contributed to a wide range of statistical areas, including survival analysis, data science, high-dimensional inference, machine learning, deep learning, spatial data analysis, random-effects models, clinical trial design, and infectious disease modeling.

He is interested in cancer genetics/genomics, radiomics, racial disparity analysis, chronic disease research and opioid overuse research. He has published more than 280 papers in major statistical journals, such as JASA, Biometrika, JRSSB, and Biometrics, as well as premier subject matter journals, such as PNAS, JAMA and JCO. His methodologic research is funded by various NIH statistical grants starting from year 2003. Li is actively involved in collaborative research in cutting-edge clinical and observational studies with researchers from the University of Michigan and Harvard University.

  • Postdoctor, Biostatistics, Harvard, 1999-2000
  • PhD, Biostatistics, University of Michigan, 1999
  • MS, Biostatistics, University of Michigan, 1996

Research Interests:
Survival analysis, data science, high-dimensional inference, machine learning, deep learning, spatial data analysis, random-effects models, clinical trial design, and infectious disease modeling, with applications in cancer genetics/genomics, radiomics, chronic disease research and opioid overuse research.

Research Projects:
  • New Statistical Methods for Modelling Cancer Outcomes
  • Causal Machine Learning in Cancer Survival by Integrating Multiple High-dimensional Observational Studies

Meng, X., Zhang, E. and Li, Y. (2025) Statistical inference on high-dimensional covariate-dependent Gaussian graphical regressions. Biometrics, in press. 

Wen, S., Li, Y., Kong, D. and Lin, H (2025) Prediction of cognitive function via brain region volumes with applications to Alzheimer’s disease based on space-factor-guided functional principal component analysis. Journal of the American Statistical Association, 120(551), 1373–1385. 

Zhang, J. and Li, Y. (2025) Multi-task learning for Gaussian graphical regressions with high dimensional covariates. Journal of Computational and Graphical Statistics, 34(3), 961–970. 

Guha, S. and Li, Y. (2024) Causal meta-analysis by integrating multiple observational studies with multivariate outcomes. Biometrics, 80(3), ujae070. 

Sun, Y., Salerno, S., Pan, Z., Yang, E., Sujimongkol, C., Song, J., Wang, X., Han, P., Zeng, D., Kang, J., Christiani, D., and Li, Y. (2024) Assessing the prognostic utility of clinical and radiomic features for COVID-19 patients admitted to ICU: challenges and lessons learned. Harvard Data Science Review, 6.1. 

Zhao, G., Ma, Y., Lin, H. and Li, Y. (2024) Evaluation of transplant benefits with the U.S. Scientific Registry of Transplant Recipients by semiparametric regression of mean residual life. Annals of Applied Statistics, 18(3), 2403-2423. 

Sun, Y., Kang, J., Haridas, C., Mayne, N., Potter, A., Yang, C., Christiani, D. and Li, Y. (2024) Penalized deep partially linear Cox models with application to CT scans of lung cancer patients. Biometrics, 80(1), ujad024. 

Salerno, S. and Li, Y. (2023) High-dimensional survival analysis: methods and applications. Annual Review of Statistics and Its Application, 10, 25-49. 

Sun, Y., Kang, J., Brummett, C. and Li, Y. (2023) Individualized risk assessment of preoperative opioid use by interpretable neural network regression. Annals of Applied Statistics, 17, 434-453. 

Zhang, E. and Li, Y. (2023) High dimensional Gaussian graphical regression models with covariates. Journal of the American Statistical Association, 118(543), 2088-2100.

Salerno, S., Messana, J., Gremel, G., Dahlerus, C., Hirth, R., Han, P., Segal, J., Xu, T., Shaffer, D., Jiao, A., Simon, J., Tong, L., Wisniewski, K., Nahra, T., Padilla, R., Sleeman, K., Shearon, T., Callard, S., Yaldo, A., Borowicz, L., Agbenyikey, W., Horton, G., Roach, J. and Li, Y. (2021) Characteristics and mortality outcomes of COVID-infected dialysis patients enrolled in Medicare. JAMA Network Open, 4(11), e2135379. doi:10.1001/jamanetworkopen.2021.35379

Email: yili@umich.edu

Address:
M2102 SPH II
1415 Washington Heights
Ann Arbor, MI 48109

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